The importance of an inclusive study design – the HepCAPP Study

Dr Kirsty Roberts

 

 

by Dr Kirsty Roberts, Senior Lecturer in Trials Methodology and Deputy Research Director EDI, Bristol Medical School, University of Bristol

Background

HepCAPP (Hepatitis C Case-finding in Primary Care Pilot) was a pilot oral swab Hepatitis C Virus (HCV) screening study which was funded by NHS England in 2019 and completed in 2023. The study invited over 98,000 people aged 40-64 registered at selected GP practices to take part. 12,216 (12.4%) consented and returned their sample to the UK Health Security Agency (UKHSA) for testing.

The study participants found the approach to testing acceptable and the uptake was better than expected. However, the study also confirmed that those identified could have been found through lower-cost targeted screening. Therefore, we recommended that oral swab HCV screening shouldn’t be rolled out in the NHS.

Were there any groups of people or communities under-represented?

The study found … Read more

What was it like attending the RCGP Annual Conference as an early career GP academic?

Dr Molly Dineen

 

 

by Dr Molly Dineen, ST2 Academic Clinical Fellow in General Practice, Centre for Academic Primary Care, University of Bristol

I was so pleased to receive a bursary from the Royal College of General Practitioners (RCGP) Severn Faculty, which enabled me to attend this year’s RCGP Annual Conference in Liverpool. I am an ST2 Academic Clinical Fellow in General Practice, and this was my first RCGP Annual Conference, as well as my first time in Liverpool!

Attending the conference was an incredible experience. I have created a short montage of my trip so that, if you haven’t been before, you can get a real taster of what it was like.

I would summarise my experience with the word ‘diversity’ and hopefully you get a sense of that from the video – diversity of experiences, diversity of sessions, diversity of people, and diversity of our profession.

There … Read more

Why do GPs prescribe benzodiazepines in young adults with anxiety?

Dr Charlotte Archer

 

 

 

By Dr Charlotte Archer, Research Fellow in Primary Care Mental Health, Centre for Academic Mental Health and Centre for Academic Primary Care, University of Bristol

Why did we do the research?

Benzodiazepines like Valium can be used to help manage the symptoms of anxiety. Research has found that the number of new prescriptions of benzodiazepines for patients with anxiety decreased between 2003 and 2018. It is likely that this is because there are some concerns in the medical community about prescribing benzodiazepines, such as dependency. However, although numbers have declined overall, rates of prescribing actually increased in young adults (those aged 18-34) from 2008 onwards.

Further, the clinical guidelines for the management of anxiety state benzodiazepines should only be used on a short-terms basis, around two to four weeks. Despite this, in 2017, just under half of the prescriptions for benzodiazepines were issued for … Read more

A global journey into primary care: insights from the NAPCRG Conference

Chloe Gamlin

 

 

 

by Chloë Gamlin, GP Academic Clinical Fellow, Centre for Academic Primary Care, University of Bristol

Attending the North American Primary Care Research Group (NAPCRG) conference for the first time proved to be an enriching experience, offering a diverse array of presentations and discussions at the forefront of primary care. Held at the Hilton in downtown San Francisco, the conference brought together healthcare providers and researchers from across the globe.

Plenaries

The opening plenary by Professor Ed Maibach underscored the role of primary care physicians in addressing climate change, emphasizing their potential to provide unbiased information. Another plenary, led by Professor Diana Greene Foster, delved into the intersection of politics and healthcare, focusing on the recent changes to US abortion law. The emotional session highlighted the resilience of healthcare professionals in supporting women’s health issues, despite differing opinions.

Distinguished papers presented in the morning sessions covered … Read more

Key insights from social science research for antibiotic stewardship interventions

 

 

By Christie Cabral, Senior Lecturer, Centre for Academic Primary Care , University of Bristol

As a social anthropologist, I’ve been investigating why antibiotics are overused for over a decade and using the insights gained to develop antibiotic stewardship interventions. For World Antimicrobial Resistance (AMR) Awareness Week, I am writing about three key insights from my research.

1. The role of ‘Explanatory Models’ for illness and treatment: the influence on consulting and prescribing behaviours

Explanatory models are the set of linked ideas or theories that we each have in our minds about an illness and the possible treatments. These inform what we do as a patient, deciding whether to consult, or as a clinician deciding whether to prescribe.

The (simplified) biomedical model for the infections is of two types: viral or bacterial. Antibiotics treat bacterial infections but are ineffective for viral infections. So, it’s simple, no one … Read more

Does increasing the Altmetric score increase citations for primary care research papers?

Dr Alex Burrell

 

 

By Dr Alex Burrell, NIHR Academic Clinical Fellow in General Practice, Centre for Academic Primary Care, University of Bristol

Dr Alex Burrell has led a study exploring the relationship between Altmetric scores and citations in primary care research journals as part of his Editorial Fellowship at the British Journal of General Practice (BJGP) and BJGP Open.

The number of times a research article is cited has traditionally been used to assess its impact and quality. Altmetric score is an alternative measure of article impact which assesses the broader societal impact of articles and includes social media, blogs, and news mentions.

Number of citations, and other measures which are based on citation count, are still most often used by researchers and universities, and are tied to financial rewards. However, academic journals and authors increasingly use parts of the Altmetric score to share and promote research.

If Altmetric … Read more

My experience as an NIHR School for Primary Care Research intern: a pharmacy student’s perspective

Loreta Valatka

 

 

by Loreta Valatka, Third Year Pharmacy Student, University of Bath

 

My internship experience

The Carry Naloxone Somerset project, led by Dr Jenny Scott, was the main focus of my 2023 research summer internship at the University of Bristol’s Centre for Academic Primary Care (CAPC). The aim of the project is to encourage people in Somerset who may experience or witness an overdose to carry naloxone – a first aid medicine that can be supplied without prescription to prevent an opioid overdose from being fatal.

Before the launch of the campaign, I analysed survey data to write a report about the possession and carriage of naloxone, as well as overdose experiences amongst Somerset Drug and Alcohol Service (SDAS) users. Post launch, I was responsible for follow-ups with the 23 pharmacies that had signed up so far. This was to ensure all participating members of the pharmacy teams … Read more

Why Test? The power of collaboration in primary care research

 

By Dr Ola Abdellatif, Primary Care Academic Collaborative (PACT) and Dr Jessica Watson, Centre for Academic Primary Care, University of Bristol

Rates of blood testing in general practice have increased over the past two decades in the UK. The reasons why are not entirely clear. Researchers from the University of Bristol, led by Dr Jessica Watson, joined forces with PACT – a collaborative of GP clinicians interested in research – to investigate who requests tests and why, and what the outcomes are. Why Test? Is their first study, which benefited from the unique access to clinical records facilitated by PACT. In this blog, Dr Ola Abdellatif, a GP trainee at the time of the study (now a salaried GP) and PACT member, together with Dr Jessica Watson, a GP and NIHR Clinical Lecturer in General Practice at the Centre for Academic Primary Care, University of Bristol and Read more

Improving papilloedema diagnosis and referral

 

 

by Dr Denize Atan, Associate Professor in Neuro-opthalmology, Neuroscience and Genetics, University of Bristol

Papilloedema is nerve swelling at the back of the eyes. It is caused by increased pressure inside the head and can be the first sign of a brain tumour or other serious health problems.

As half the people with a brain tumour have no symptoms, optometrists (trained eye care professionals who work at optician practices) may be the first to notice nerve swelling in someone during a routine eye test.

The importance of detecting papilloedema has been highlighted by recent high profile cases in the media.

The ‘Improving the Diagnostic accuracy of referrals for Papilloedema’ (DIPP) Study is funded by the National Institute for Health and Care Research (NIHR) to develop a set of guidelines and educational materials for optometrists and GPs that will help them to diagnose papilloedema more accurately … Read more